Police say he has serious injuries.
Officers are appealing for witnesses to the crash outside a property on the B480, Lower Road in Garsington.
It happened at around 11.55pm on Friday (30/8).
The driver of a silver Kia Sportage, a man in his forties, was taken to hospital, were he remains receiving treatment.
No one in the house was injured.
Senior investigating officer, PC Sarah Davies, said: “I am appealing for anyone who may have witnessed this incident to please come forward.
“I would also urge any motorists who were in the local area around the time of the collision to check any dash-cam footage in case it may have captured something that could assist with the investigation."
Anyone with information can contact police on the non-emergency number 101 quoting reference number 43190268765.